OSW-1

  • CAS：145075-81-6
  • purity：99%
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Details

Export Top Purity OSW-1 145075-81-6 In Stock

  • Molecular Formula: C47H68 O15
  • Molecular Weight: 873.048
  • Vapor Pressure: 0mmHg at 25°C 
  • Boiling Point: 932.5 °C at 760 mmHg 
  • PKA: 12.65±0.70(Predicted) 
  • Flash Point: 267 °C 
  • PSA： 216.97000 
  • Density: 1.31 g/cm3 
  • LogP: 4.02410 

OSW-1(Cas 145075-81-6) Usage

InChI:InChI=1/C47H68O15/c1-24(2)8-15-34(50)25(3)47(55)37(21-33-31-14-11-28-20-29(49)16-18-45(28,5)32(31)17-19-46(33,47)6)60-44-41(59-26(4)48)39(36(52)23-58-44)62-43-40(38(53)35(51)22-57-43)61-42(54)27-9-12-30(56-7)13-10-27/h9-13,24-25,29,31-33,35-41,43-44,49,51-53,55H,8,14-23H2,1-7H3/t25-,29-,31+,32-,33-,35-,36+,37-,38+,39+,40-,41-,43+,44+,45+,46+,47-/m1/s1

145075-81-6 Relevant articles

A new synthesis of potent antitumor saponin OSW-1 via Wittig rearrangement

Tsubuki, Masayoshi,Matsuo, Sohichiro,Honda, Toshio

, p. 229 - 232 (2008)

OSW-1 and its analogues in which thiophe...

OSW Saponins: Facile synthesis toward a new type of structures with potent antitumor activities

Shi, Bingfeng,Tang, Pingping,Hu, Xiaoyi,Liu, Jun O.,Yu, Biao

, p. 10354 - 10367 (2007/10/03)

OSW saponins, featuring a 16β,17α-dihydr...

Synthesis of analogues of a potent antitumor saponin OSW-1

Morzycki, Jacek W.,Wojtkielewicz, Agnieszka,Wolczynski, Slawomir

, p. 3323 - 3326 (2007/10/03)

A series of side chain analogues (5a-e),...

Total synthesis of the anticancer natural product OSW-1

Yu, Wensheng,Jin, Zhendong

, p. 6576 - 6583 (2007/10/03)

The highly potent anticancer natural sap...

145075-81-6 Process route

C<sub>77</sub>H<sub>116</sub>O<sub>18</sub>Si<sub>2</sub>
335197-29-0

C77 H116 O18 Si2

3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside}
145075-81-6

3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside}

Conditions
Conditions Yield
C77H116O18Si2; With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; at 25 ℃; for 12h;
With bis(acetonitrile)palladium(II) dichloride; In water; acetone; at 25 ℃; for 2h; Further stages.;
81%
C77H116O18Si2; With water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 25 ℃; for 12h;
With bis(acetonitrile)palladium(II) dichloride; water; In acetone; at 25 ℃; for 2h; Further stages.;
81%
C<sub>71</sub>H<sub>124</sub>O<sub>15</sub>Si<sub>4</sub>

C71 H124 O15 Si4

3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside}
145075-81-6

3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside}

Conditions
Conditions Yield
With water; dichloro bis(acetonitrile) palladium(II); In acetone; at 20 ℃;
82%

145075-81-6 Upstream products

  • 219906-58-8
    219906-58-8

    C73 H128 O16 Si4

  • 335197-29-0
    335197-29-0

    C77 H116 O18 Si2

  • 478286-99-6
    478286-99-6

    C66 H112 O15 Si3

  • 870626-35-0
    870626-35-0

    C71 H126 O15 Si4

145075-81-6 Downstream products

  • 100-09-4
    100-09-4

    4-methoxybenzoic acid

  • 145075-83-8
    145075-83-8

    3β,17α-dihydroxy-16β-[(O-β-D-xylopyranosyl-(1→3)-α-L-arabinopyranosyl)oxy]cholest-5-en-22-one

  • 1593111-61-5
    1593111-61-5

    C58 H80 N4 O19 S

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