Di-tert-butyl dicarbonate

  • CAS：24424-99-5
  • purity：99%
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1.What is the Di-tert-butyl dicarbonate ?

Di-tert-butyl dicarbonate (Boc2O) is a widely used reagent for introducing protecting groups in peptide synthesis. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

<i>tert</i>-butyl alcohol
75-65-0

tert -butyl alcohol

di-<i>tert</i>-butyl dicarbonate
24424-99-5

di-tert -butyl dicarbonate

Conditions
Conditions Yield
bis(trichloromethyl) carbonate; tert-butyl alcohol; With triethylamine; In hexane; at -5 ℃;
With sodium hydroxide; In hexane; water; at 10 ℃; for 5.33333h; Reagent/catalyst; Temperature;
72%
potassium <i>tert</i>-butylate
865-47-4

potassium tert -butylate

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

di-<i>tert</i>-butyl dicarbonate
24424-99-5

di-tert -butyl dicarbonate

Conditions
Conditions Yield
With pyridine; sulfuric acid; sodium hydrogencarbonate; In hexane; water;
89%
In hexane; water;
87%
In water; N,N-dimethyl-formamide; toluene;
24%

2.What is the CAS number for Di-tert-butyl dicarbonate ?

The CAS number of Di-tert-butyl dicarbonate is 24424-99-5.

More information of Di-tert-butyl dicarbonate 24424-99-5 are:

CAS?Number

24424-99-5

Density

1.054 g/cm3

Melting Point

22-24 °C

Boiling Point

235.8 °C at 760 mmHg

Flash Point

103.7 °C

Vapor Pressure

0.7mmHg at 25°C

Refractive Index

n20/D 1.409(lit.)

HS CODE

29209010

PSA

61.83000

LogP

2.87320

3.What are another words for Di-tert-butyl dicarbonate ?

Synonyms?for?Di-tert-butyl dicarbonate 24424-99-5:tert-Butoxycarbonyl anhydride;Bis(tert-butoxycarbonyl)oxide;Pyrocarbonic acid di-tert-butyl ester;Boc Anhydride;tert-butoxycarbonyl tert-butyl carbonate;Di(tert-butyl) carbonate;Dicarbonic acid, bis(1,1-dimethylethyl) ester;tert-Butyl dicarbonate;BOC-acidanhydride;Di-tert-butyl dicarbonate (Boc Anhydride);Di-tert-butyl dicarbonate(DIBOC);Di-BocDi-t-butyl Dicarbonate;Di-t-butyl pyrocarbonate;

4.What is the molecular formula of Di-tert-butyl dicarbonate?

The chemical formula of ?Di-tert-butyl dicarbonate is?C10H18O5 which containing 10 Carbon atoms,18 Hydrogen atoms and 5 Oxygen atoms,and the molecular weight of??Di-tert-butyl dicarbonate?is 218.25.

5.What is Di-tert-butyl dicarbonate (24424-99-5) used for?

Di-tert-butyl dicarbonate (Boc-anhydride) is a widely used reagent in organic chemistry. It is an extremely efficient reagent to introduce the tert-butoxycarbonyl (BOC) protecting group for the amine functionality. It is also an efficient tert-butoxycarbonylating agent for alcohols and thiols. Di-tert-butyl dicarbonate is utilized for various synthetic transformations due to its versatility and ease of introduction and cleavage as a protecting group.

InChI:InChI=1/C10H18O5/c1-8(2,3)11-7(10)12-9(4,5)6/h1-6H3

Relevant articles related to Di-tert-butyl dicarbonate:

Article

Source

Method for synthesizing di-tert-butyl dicarbonate ester by adopting phase transfer catalytic method

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Paragraph 0018-0041, (2018/12/02)

Production technology of tert-butyl pyrocarbonate

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Paragraph 0002; 0003, (2017/07/12)

6.Buy Di-tert-butyl dicarbonate with the best price .

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